Believe it or not, there is a natural ingredient from Europe that can help convert the way your legs feel and the way you feel about the circulation in your legs. Either we perceive it or not, the circulation in our legs can have a huge influence on how we feel and what we do everyday and maybe even more so every evening. The relax level of our legs, or best said, their pain level at the end of the day can adversely influence our communal life and fitness activities - not to mention adversely affecting our sleep. If our legs felt best maybe we would find it easier to do the things we'd love to do, but find it so difficult to muster the motivation. As if the way our legs can feel at the end of day isn't inspiring enough, the changes in the circulation in our legs as we age can seem even more hopeless and discouraging. Now add to that the seeming conspiracy among fashion designers to have us exposing even larger portions of our aging legs and we have a problem that over 80 million Americans with varicose veins understand all too well. (1).
Unfortunately, about half of all American women will invent varicose or spider veins at some point in their lives (2). Not only are they unsightly, these leg problems can also cause critical discomfort. Typically, varicose veins are characterized by bulging, blue, sometimes painful and inflamed veins that appear primarily in the calves and thighs. Spider veins, on the other hand, show up as a web of fine lines that can make your legs look like a road map.
Pregnancy Care Centre
While age and heredity play a role in the improvement of varicose and spider veins, weight gain, pregnancy, menopause and the use of hormone exchange therapy can also trigger these vein problems. Development matters worse, chronic inactivity, standing for long periods of time or habitually crossing your legs can make you more prone to injured veins (2).
Conventional treatments comprise surgical stripping, injecting the veins with a chemical irritant or zapping them with lasers. While these approaches can remove existing varicose or spider veins, they will not prevent new ones from developing, since these high-tech treatments do not address the basal problem of poor circulation. Worse yet, these procedures can also cause infection, scarring, nerve damage and pain (26). If these radical treatments are not an choice for you, you'll be happy to hear that there is a natural arrival that not only improves the appearance of these ropy, bulging veins, it also fosters leg condition to prevent future problems.
Veins Explained
To understand how varicose veins develop, you need to know a itsybitsy bit about how blood moves straight through the body. Essentially, there are two types of major circulatory vessels in the body: the arteries, which channel blood from the heart to the extremities, and the veins, which bring blood from the extremities back to the heart. Of all the veins in your body, leg veins work the hardest to carry blood back to the heart. To accomplish this difficult task, your legs are equipped with specially designed one-way valves that keep the blood inspiring in the right direction. As efficiently as these valves work, your legs still fight a constant battle against the natural pull of gravity. If the veins can't move the blood efficiently or the one-way valves that prevent the blood from backwashing fail to close properly, blood collects in the legs. This pooling of blood then stretches the vein, causing swelling and injury to the vein's walls (3).
Depending on the extent of the enlargement, these veins can show up as Either spider or varicose veins. Spider veins are broken capillaries and small veins that appear as jagged red, blue or purple lines on the surface of the skin. While they aren't painful, they can be very unattractive. Varicose veins, on the other hand, are thick veins that run deeper under the skin. They are far larger and much less inspiring than spider veins - and they can make your legs feel fatigued, heavy, achy or even itchy. Varicose veins can also cause burning, throbbing, cramping and restlessness.
While these conditions aren't usually dangerous, severe cases can lead to chronic venous insufficiency - a persistent inability of the leg veins to adequately return blood back to the heart (4). Varicose veins are also linked with the improvement of skin ulcers or a chronic inflammation of a vein - a condition known as phlebitis. Phlebitis is often accompanied by formation of a blood clot, a hazardous situation since the clot can move from the leg vein and trip to the lungs (2).
Get a Leg Up with Diosmin
Your strategy for battling vein problems plainly is twofold: improving circulation and strengthening the vein walls. The first and simplest quantum to heighten blood flow is to counteract gravity. Standing or sitting all day makes it harder for blood to move up from the legs and back to the heart. But taking a few minutes to rest with your legs higher than your heart each day allows gravity to help return blood to the heart.
Getting in shape can also help relax varicose and spider veins - and it can even prevent new ones from forming. As we age we lose muscle tone, which adversely affects the condition of our legs. Yet adopting a consistent practice agenda promotes good circulation and can help to keep our leg muscles, and the blood vessels in our legs, toned. Walking, weight training, low-impact aerobics and swimming enlarge the legs and circulatory system, and help to sell out the throbbing and aching often linked with varicose veins.
What you eat can also ease unsightly veins. A low-fat diet filled with fruits, vegetables, beans, legumes and whole grains add key nutrients and fiber to your diet. Eating a fiber-rich diet reduces the chances of constipation which can lead to varicose veins. Constipation restricts the blood as it returns to the torso straight through the deep veins in the legs. Straining to have a bowel movement closes off the deep veins in the legs and restricts the flow of blood as it returns to the torso. As the blood backs up, it takes another policy straight through superficial veins, thus the blue streaks in the legs. Eating a fiber-rich diet alleviates and prevents constipation, helping to avoid the damage to the vascular theory that can result. In increasing to fiber, a diet high in fruits and vegetables also ensures sufficient intake of nutrients and phytonutrients, which also help tonify the blood vessels. As a bonus, a salutary diet and practice agenda can also jump-start weight loss - an leading consideration since carrying too much weight creates extra pressure on your heart and blood vessels, interfering with salutary circulation (2).
To enlarge the veins themselves, take a tip from the Europeans. From Austria to France to Italy, women and their doctors have relied on Diosmin for more than 30 years to treat circulatory problems affecting the legs - and with good reason. Diosmin is a unique bioflavonoid derived from citrus fruits and is closely linked to other citrus bioflavonoids such as hesperiden, quercetin, and rutin (5). Clinical trials have shown that Diosmin is very efficient in boosting circulation and strengthening the veins in the legs (5). Not only does this heighten existing varicose and spider veins, it can also sell out the likelihood of future problems.
What makes Diosmin so extraordinary is its power to specifically target the blood vessels in the legs. Diosmin improves both blood vessel elasticity and microcirculation while relieving pain and inflammation by inhibiting pro-inflammatory prostaglandins and thromboxanes (21,24). Because of its direct performance on the integrity of vein walls, Diosmin also reduces the whole of fluid that leaks out of them (21,22). Diosmin's protective benefits do not stop there. Because it is a potent anti-oxidant, Diosmin decreases lipid peroxidation and reduces free radical damage that can undermine vein condition (23, 27).
In one clinical trial, population who suffered from pain and swelling due to varicose veins experienced critical correction in their symptoms after taking Diosmin for a few months (6). A recap of studies also found that, among more than 5,000 patients with vein disorders, the vast majority not only saw a discount in their discomfort, they undoubtedly saw the swelling in their calves and ankles disappear (7). Across the board, explore shows that a daily dose of 500 to 1,000 mg of Diosmin improves the condition of leg veins and brings broad relief from pain, night cramps and leg heaviness (8,9,10,11). Both short- and long-term use of this very efficient natural ingredient comes without any side effects. It is also so safe that you need not worry about adverse interactions of Diosmin with drugs, foods, lab tests or interactions with diseases or conditions. (5).
Help for Hemorrhoids
Because Diosmin reduces swelling and bolsters vein health, it can also help population suffering with hemorrhoids - those uncomfortable varicose veins that form in the lower rectum and anus. Along with Development it painful to sit, hemorrhoids can itch, bleed or protrude - and almost half of all Americans suffer from them by the time they turn 50 (12). Allinclusive explore conclusively shows that Diosmin can safely alleviate the pain, inflammation and bleeding of hemorrhoids (13,14,15). Best of all, it offers quick relief, often working its magic within a week or two (16). Plus, Diosmin reduces the risk of a relapse (17).
Diosmin for Cancer?
While no one questions Diosmin's efficacy for treating varicose and spider veins or hemorrhoids, scientists have begun exploring other ways this potent flavonoid may boost health. Their main focus - cancer prevention - especially oral and skin cancers.
Researchers haven't conclusively identified the cancer-fighting component in Diosmin, but initial experiments show that this flavonoid inhibits the proliferation of cancer cells (18). In two studies pitting Diosmin against other flavonoids like rutin, grapeseed citation and red wine, Spanish investigators found that Diosmin was considerably more efficient at reducing the whole of metastatic melanoma cells (a potentially deadly type of skin cancer cells that spread straight through the body) than any of the other flavonoids tested (19,20). Other studies have found that Diosmin puts the brakes on the spread of cancer cells in the mouth (25).
Although it could be years before science conclusively proves Diosmin's cancer benefit, this nutrient can't be beat for supporting vein health. Along with taking supplemental Diosmin, there are any straightforward strategies you can employ to encourage salutary circulation. Eating a high-fiber, anti-oxidant rich diet and getting plentifulness of practice can help keep veins in top form. And remember to take a break and put your feet up every now and again.
References:
1. American community for Dermatoloic Surgery.
2. National Women's condition data Center. U.S. Agency of condition & Human Services.
3. American College of Phlebology.
4. community for Vascular Surgery.
5. Diosmin Monograph. Alternative treatment Review. 2004;9(3):308-311.
6. Ting Ac, et al. Clinical and hemodynamic outcomes in patients with chronic venous insufficiency after oral micronized flavonoids therapy. Vascular Surgery. 2001;35(6):443-447.
7. Ramelet Aa. Daflon 500 mg: symptoms and edema clinical update. Angiology. 2005;56 Suppl 1:S25-S32.
8. Bergan Jj. chronic venous insufficiency and the therapeutic effects of Daflon 500 mg. Angiology. 2005; 56 Suppl 1:S21-S24.
9. Nicolaides An. From symptoms to leg edema: efficacy of Daflon 500 mg. Angiology. 2003;54 Suppl 1:S33-S44.
10. Smith Pc. Daflon 500 mg and venous leg ulcer: new results from a meta-analysis. Angiology. 2005; 56 Suppl 1:S33-S39.
11. Jantet G. chronic venous insufficiency: worldwide results of the Relief study. Reflux estimate and quality of life correction with micronized Flavonoids. Angiology. 2002;533:245-256.
12. National Institutes of Health.
13. Lyseng-Williamson Ka, et al. Micronised purified flavonoids fraction: a recap of its use in chronic venous insufficiency, venous ulcers and haemorrhoids. Drugs. 2003;63(1):71-100.
14. Meshikhes Aw. Daflon for haemorrhoids: a prospective, multi-centre observational study. Surgeon. 2004;2(6):335-338.
15. Kecmanovic D, et al. Phlebodia (diosmine): a role in the administration of bleeding nonprolapsed hemorrhoids). Acta Chirurgica Iugoslavica. 2005;52(1):115-116.
16. Diana G, et al. performance of purified diosmin in the treatment of hemorrhoids. La Clinica Terapeutica. 2000;151(5):341-344.
17. Misra Mc, et al. Randomized clinical trial of micronized flavonoids in the early operate of bleeding from acute internal haemorrhoids. British Journal of Surgery. 2000;87(12):1732-1733.
18. Browning Am, et al. Flavonoid glycosides inhibit oral cancer cell proliferation - role of cellular uptake and hydrolysis to the aglycones. Journal of Pharmacy and Pharmacology. 2005;57(8):1037-1042.
19. Martinez C, et al. treatment of metastatic melanoma B16F10 by the flavonoids tangeretin, rutin, and diosmin. Journal of Agricultural and Food Chemistry. 2005;53(17):6791-6797.
20. Martinez C, et al. The corollary of the flavonoids dioxmin, grapeseed citation and red wine on the pulmonary metastatic B16F10 melanoma. Histology and Histopathology. 2005;20(4):1121-1129.
21. Ramelet Aa. Clinical benefits of Daflon 500 mg in the most severe stages of chronic venous insufficiency. Angiology. 2001;52 Suppl 1:S49-56.
22. Cyrino Fz, et al. Micronization enhances the protective corollary of purified flavonoidsfraction against postischaemic microvascular injury in the hamster cheek pouch. Clinical and Experimental Pharmacology & Physiology. 2004;31(3):159-162.
23. Bergan Jj, et al. Therapeutic arrival to chronic venous insufficiency and its complications: place of Daflon 500 mg. Angiology. 2001;52 Suppl 1:S43-7.
24. Katsenis K. Micronized purified flavonoids fraction (Mpff): a recap of its pharmacological effects, therapeutic efficacy and benefits in the administration of chronic venous insufficiency. Current Vascular Pharamcology. 2005;3(1):1-9.
25. Browning Am, et al. Flavonoid glycosides inhibit oral cancer cell proliferation - role of cellular uptake and hydrolysis to the aglycones. Journal of Pharmacy and Pharmacology. 2005;57(8):1037-1042.
26. National Women's condition data Center. U.S. Agency of condition and Human Services, Office on Women's Health.
27. Villa P, et al. Protective corollary of diosmetin on in vitro cell membrane damage and oxidative stress in cultured rat hepatocytes. Toxicology. 1992;73:179-189.
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